Basic Information
VIS ID
TVIS44012726
Fusion event
HTLV-1-LINC02588 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
27139591/26670385 (Hg38)
End
27139591/26670385 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02588
Nearest miRNA
hsa-mir-208a/Upstream/2526820; hsa-mir-1185-1/Downstream/238257;
Nearest TSS
ENST00000550708/Upstream/33144; ENST00000548328/Downstream/64969;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/465113, chr14-CpG: 203/Downstream/2095298
Nearby gene
NOVA1(-72631) ;
Upstream sequence
ATAAAGCTTACATTTTCTGAACTCAGGTACtttaaaaaatgtgaactatttttttctagagcagttttacaacaaaattgagtggaaaatagagattctc
Downstream sequence
tatatacatctttcccccatgtatgcccaatcttctccgctatcaaaacccACAGGATATATCCCATATAAtttcatagtaatctgcatttaagatgcct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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