Basic Information
VIS ID
TVIS44012740
Fusion event
HTLV-1-LOC100130207 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p26.2
Reference genome
GRCh37/hg19
Start
3743900/3702216 (Hg38)
End
3743900/3702216 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC100130207
Nearest miRNA
hsa-let-7g/Downstream/1547961;
Nearest TSS
ENST00000440867/Upstream/74920; ENST00000472075/Downstream/95998;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/522283, chr3-CpG: 190/Downstream/96613
Nearby gene
LRRN1(+97221) ;
Upstream sequence
GCCTATTAGCATATCAGAGGTTCACACGCACACTAATAATGTCAGCGGTGCTTCACCTGCTCCATTCCTCGCCTAGTCCATGTCTTTTTAAACAGAGAAA
Downstream sequence
AAGATCAAAAGAACAGTAAATTGCCCTGCACGGCAACCAAATCTGAAGATACATTATAATGACAAACTTTTCTTCAATCCAAAATGAACATGCTTCGTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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