VISDB Viral Integration Site DataBase

VIS ID

TVIS44012745

Fusion event

HTLV-1-PRKAA1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr5

Cytoband

p13.1

Reference genome

Start

End

40787149/40787047 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-19b-3p ; hsa-mir-148b-3p ; hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-30a-5p ; hsa-mir-652-3p ; hsa-mir-30e-5p ; hsa-mir-29b-3p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-1-5p ; hsa-mir-154-3p ; hsa-mir-487a-3p ; hsa-mir-3149 ; hsa-mir-6833-5p ; hsa-mir-297 ; hsa-mir-675-3p ; hsa-mir-1298-5p ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-3613-5p ; hsa-mir-3190-3p ; hsa-mir-567 ; hsa-mir-4781-3p ; hsa-mir-299-3p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-8063 ; hsa-mir-4698 ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-301b-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301a-3p ; hsa-mir-130a-3p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-561-3p ; hsa-mir-4638-3p ; hsa-mir-3690 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-451b ; hsa-mir-548e-5p ; hsa-mir-19a-3p ; hsa-mir-33a-5p ; hsa-mir-9-5p ; hsa-mir-137

Nearest miRNA

hsa-mir-10397/Upstream/2229486; hsa-mir-103a-1/Downstream/13164457;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/30892, chr5-CpG: 100/Downstream/10502

Nearest cancer related gene

PRKAA1(TSG, No orient, 0)

Upstream sequence

actttgtctcaaacaaacaaaaagaaacagaaaaagaaatggtaaagaaacttcttcaagctgaataaagaagacactaatgagtgacaggaaaacatga

Downstream sequence

aaagtataaaactcactggaaaaagtaagtatactgtcaaccccaaaacacactaatactgtaatggtggtaagtaaatgaattatatatctagtataaa