Basic Information
VIS ID
TVIS44012782
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42382457/41857750 (Hg38)
End
42382457/41857750 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6216498; hsa-mir-107/Downstream/1139813;
Nearest TSS
ENST00000439456/Upstream/3404569; ENST00000442306/Downstream/327589;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2914644, chr10-CpG: 184/Downstream/253283
Upstream sequence
cattgcattccatgccattccattccattccactccattccaatacataccactcgggttgattccattcctttccataccattccattccattccattg
Downstream sequence
cattccactcgggttgattccattctattccattccattccattccattccactccactgcattccattgcattcccttccactggggttgtttcctttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate