Basic Information
VIS ID
TVIS44012820
Fusion event
HTLV-1-chr4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
76111925/75186715 (Hg38)
End
76111925/75186715 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/8909787; hsa-mir-1243/Downstream/1386853;
Nearest TSS
ENST00000502981/Upstream/101998; ENST00000512043/Downstream/167361;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/251994, chr4-CpG: 56/Downstream/327510
Nearby gene
PARM1(+136600) ;
Nearest cancer related gene
PARM1(OG, +136600) ;
Upstream sequence
agcttgccatgagccgagattgtgccattgcactccagcctgggcgacagagcgaaactcagtctcaaaaaaaaaaaaaaaaaagaatggccataataaa
Downstream sequence
caaatcaaaagataataaatgttggcatggatgtggtaaaaatgggaacactattacactgctggtgggaatgtaaactgctacagtcactatgcaaaac
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate