Basic Information
VIS ID
TVIS44012827
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
112927545/113208698 (Hg38)
End
112927545/113208698 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/471517; hsa-mir-12124/Downstream/223420;
Nearest TSS
ENST00000440867/Upstream/40879; ENST00000462425/Downstream/2305;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/188892, chr3-CpG: 93/Downstream/2892
Nearby gene
BOC(+2767) ;
Nearest cancer related gene
BOC(OG, +2767) ;
Upstream sequence
ACAATAAACATATCTGAGGTACCAACAGTGTGCTTGATGCCGCCAGCAGAATTAAGTCCTCTTTATTAAGCTGTGATCTGCATTCTGCCTAAACTATAAG
Downstream sequence
AAAGGTGAGCAGCAggccgggagcagtggctcatgcctgtaaccccagcactttgggaggctgaggcgggctgatcacctgaggtcaggagttcgagacc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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