Basic Information
VIS ID
TVIS44012864
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
53324811/55247450 (Hg38)
End
53324811/55247450 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/4478720; hsa-mir-1250/Downstream/1643820;
Nearest TSS
ENST00000595228/Upstream/216643; ENST00000572234/Downstream/17562;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/8613, chr17-CpG: 88/Downstream/17387
Nearby gene
HLF(+17510) ;
Nearest cancer related gene
HLF(OG, +17510) ;
Upstream sequence
ATGACTGCCATGAACCAGTGGATCAAGGAAACTTCACTGAGCTGAACCCTGAGTGACTTGAAAAAGCCTTTCATCCAAAGatcctcaacccctctttctc
Downstream sequence
tgtcacactccatatccaccccacagaaaatcctgctTAGGTGTTTGCGTTTTAAATTTGTGTTAATACTATTATTGTTGTGTGTGTGCTGAGGGCATCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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