Basic Information
VIS ID
TVIS44012892
Fusion event
HTLV-1-LOC105378657 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
38843691/38378019 (Hg38)
End
38843691/38378019 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105378657
Nearest miRNA
hsa-mir-12136/Upstream/288690; hsa-mir-101-1/Downstream/2376336;
Nearest TSS
ENST00000473358/Upstream/163252; ENST00000634732/Downstream/96856;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/330049, chr1-CpG: 42/Downstream/200474
Nearby gene
LINC01343(No orient, 163252)
Upstream sequence
CTTTAGGTCACCATCTCTGTTTAGGTGCAGAGGTAGATTTATCTGATGATGCAGTATTGGAGCTGTTCCGACTTTCTCCATTTTCCAGCCTTGTCACCGG
Downstream sequence
GACCTCCCTCCACTCCTTCTGTCCAAGGCTGAGCTCTCCCGGGTGCACTCCCAGTGGCCCCTCACCCCTTTCTAGCCCCAGCCATGCCTCCTTTGTCTGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate