Basic Information
VIS ID
TVIS44012913
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
97299792/96906014 (Hg38)
End
97299792/96906014 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7i/Upstream/1596030; hsa-mir-1178/Downstream/585895;
Nearest TSS
ENST00000382841/Upstream/258039; ENST00000557092/Downstream/1209;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/416055, chr12-CpG: 64/Downstream/1010
Nearby gene
NEDD1(+1209) ;
Upstream sequence
tacatacacattacgtctatatacacaaatacagtgcttagtaaagtgttcaataaatatctatttttatATGTATAACTAGtattatatcatataatat
Downstream sequence
gtatatattatattacatgtattattatatatattTTCATATAGTCTAGTCTCAATTTTCCTGCTGGCTTCAATTTTCAGAGATTTAATTAATTGCCCTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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