Basic Information
VIS ID
TVIS44012921
Fusion event
HTLV-1-NCOR1P2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
21538605/22067945 (Hg38)
End
21538605/22067945 (Hg38)
Orient
+
Location type
Intronic
Target gene
NCOR1P2
Nearest miRNA
hsa-mir-1180/Upstream/2723371; hsa-mir-10226/Downstream/5225965;
Nearest TSS
ENST00000595228/Upstream/375422; ENST00000578881/Downstream/198384;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/223482, chr17-CpG: 22/Downstream/149324
Upstream sequence
ctagcctcaatctcctgacctcgtgatccacccgcttcggcctcccaaagtgctgggattacaagtgtgagccatcgcgcctgaccaattttcacttatg
Downstream sequence
ttttcctctctaagttttataattataggtctttcatttaggtaaattacctattttgaattaaaattttatatgtggtgtggtaagcattgagtttcag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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