Basic Information
VIS ID
TVIS44012932
Fusion event
HTLV-1-chr5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
54054632/54758804 (Hg38)
End
54054632/54758804 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA5H
Nearest miRNA
hsa-mir-10397/Upstream/807205; hsa-mir-103a-1/Downstream/411728;
Nearest TSS
ENST00000502646/Upstream/240939; ENST00000512089/Downstream/199042;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/239328, chr5-CpG: 84/Downstream/124731
Nearby gene
LOC102467080(No orient, 14546)
Upstream sequence
ATTTTAGAACTACACAAAATGAAATGACAGTCTACATTTTACAGTAAATTAAATAAAAGCTAATATCATAtactttatcttattttgttttatatctttt
Downstream sequence
tattttTTCTAAGAAACTGAGAAATGGGTTGTGTGATTTTGCAGAACTTATTTGTTAAAGAACTGAATCATAATTGCTAAACTAAGAAATTCTTGCAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate