Basic Information
VIS ID
TVIS44012980
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
13961769/13940222 (Hg38)
End
13961769/13940222 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/1776455; hsa-let-7a-2/Downstream/2029311;
Nearest TSS
ENST00000527297/Upstream/15359; ENST00000591785/Downstream/22467;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/271045, chr11-CpG: 185/Downstream/22297
Nearby gene
SPON1(+22415) ;
Upstream sequence
GTTGAACAGCCTGACTTTGTCACTGTGATTCACATTCCTCTCATCTCTTCTTGATGACCTGGCTGCCCCGTCACTCTGGCCCCAGGGGATACTGTTTTTC
Downstream sequence
CTTTAACATCCTTACTTCATTCTGAGTGCTGCTTCAGAAGGAAGGGGCCCACAGCTCTCTGCCAATGATTTAATTCCAAATACTCTTTTTTTCATCGCCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate