Basic Information
VIS ID
TVIS44012984
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
115529879/115659161 (Hg38)
End
115529879/115659161 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11G ; FRA11B
Nearest miRNA
hsa-mir-10392/Upstream/2209073; hsa-let-7a-2/Downstream/2984839;
Nearest TSS
ENST00000527297/Upstream/20598; ENST00000539305/Downstream/497;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/153998, chr11-CpG: 46/Downstream/118
Nearby gene
LINC00900(No orient, 96172)
Upstream sequence
TTGTCTGGAGTGTCTGTCATCAGGAATTTGGCCCGACACCCACGCGCTCCGCAAGGGAGCCAGGGGGAGGGGAAGGACACAGGAGACAGAACTCCTGGGG
Downstream sequence
GAGAGAATCTGCCTAGCAGGCGGCTCTCCCCTGCTCCCCCACCGAGCACAGACCGTGGGAGGGGACCCTGCGGGAGGAGGCTGCTTCAGTCTCCAGAGAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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