Basic Information
VIS ID
TVIS44013028
Fusion event
HTLV-1-LPP integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q28
Reference genome
End
188498782/188780994 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-142-3p ; hsa-mir-758-5p ; hsa-mir-3190-3p ; hsa-mir-548aw ; hsa-mir-6079 ; hsa-mir-4762-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4452 ; hsa-mir-376a-5p ; hsa-mir-3192-3p ; hsa-mir-4684-3p ; hsa-mir-656-5p ; hsa-mir-4502 ; hsa-mir-4680-3p ; hsa-mir-5187-3p ; hsa-mir-4427 ; hsa-mir-491-3p ; hsa-mir-7156-3p ; hsa-mir-514b-5p ; hsa-mir-513c-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4729 ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-4752 ; hsa-mir-620 ; hsa-mir-3911 ; hsa-mir-1270 ; hsa-mir-7847-3p ; hsa-mir-4697-3p ; hsa-mir-4683 ; hsa-mir-4289 ; hsa-mir-4302 ; hsa-mir-6733-3p ; hsa-mir-574-5p ; hsa-mir-297 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-511-3p ; hsa-mir-6782-5p ; hsa-mir-3936 ; hsa-mir-6820-3p ; hsa-mir-3164 ; hsa-mir-4765 ; hsa-mir-1236-5p ; hsa-mir-3174 ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-6505-3p ; hsa-mir-617 ; hsa-mir-627-3p ; hsa-mir-942-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4662b ; hsa-mir-4647 ; hsa-mir-4426 ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6726-3p ; hsa-mir-4294 ; hsa-mir-130b-5p ; hsa-mir-6812-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-4793-5p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-15a-3p ; hsa-mir-6888-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-1265 ; hsa-mir-191-5p ; hsa-mir-2392 ; hsa-mir-4327 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4740-3p ; hsa-mir-4742-5p ; hsa-mir-5093 ; hsa-mir-5186 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-7846-3p ; hsa-mir-1827 ; hsa-mir-19a-5p ; hsa-mir-19b-1-5p ; hsa-mir-19b-2-5p ; hsa-mir-2052 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4666a-3p ; hsa-mir-4709-3p ; hsa-mir-4722-5p ; hsa-mir-485-5p ; hsa-mir-665 ; hsa-mir-6746-5p ; hsa-mir-6771-5p ; hsa-mir-6808-5p ; hsa-mir-6884-5p ; hsa-mir-6893-5p ; hsa-mir-7160-5p ; hsa-mir-7849-3p ; hsa-mir-940
Nearest miRNA
hsa-let-7g/Upstream/92128; hsa-mir-3137/Downstream/1048928;
Upstream sequence
AGGAGACACTTTCAGCTATTAGGCAATGGATCACACTTTCAAAGGAGATTGAGCAATCTCCTCATCAAGTTGTACTTAGAGCACAAATCTGGTGCCAAAA
Downstream sequence
GGCACTACCGGATTCAGACTGACAGCACTGAGAGTTTTGAGTGAAAGGGAAGTTAGACTGGTGTTATGTGTATTCACTGGGAGGAACTCACCGGGAGAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate