Basic Information
VIS ID
TVIS44013060
Fusion event
HTLV-1-LOC105371646 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
183428662/183459527 (Hg38)
End
183428662/183459527 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371646
Nearest miRNA
hsa-mir-101-1/Upstream/3021137; hsa-mir-1182/Downstream/9256801;
Nearest TSS
ENST00000473358/Upstream/40925; ENST00000493609/Downstream/12689;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/40998, chr1-CpG: 62/Downstream/12963
Nearby gene
SMG7-AS1(No orient, 1349)
Upstream sequence
CAAAACTATCTTTCATTCATTTTGTAGGCAAGCTTTCTAAAAACCACACAAGtagctttaattactatctaactgctgatgactcccaaagctacaactc
Downstream sequence
tagtacagatttctctcatgttctccagatacacaagttttctcaaccccagacaaatgtagttcagcatgtccaaaataaattcattatctccacatcc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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