Basic Information
VIS ID
TVIS44013129
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
11080402/11177085 (Hg38)
End
11080402/11177085 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA17A
Nearest miRNA
hsa-mir-1253/Upstream/2990081; hsa-mir-10226/Downstream/904814;
Nearest TSS
ENST00000595228/Upstream/298892; ENST00000577346/Downstream/64178;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/446912, chr17-CpG: 244/Downstream/63085
Nearby gene
SHISA6(+64338) ;
Upstream sequence
ttattcatgcctcccccttttagaccatatagggtaactttctgatgttgccatggcatttgtaaaccgtcatggcactggtgggagtgtatcagcgagg
Downstream sequence
atgaccagacgtcactcttgtcgccatcttggttttggtggggtttagctggcttctttactgcaaactgttttatcagcaaggtctttatgacctgtat
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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