Basic Information
VIS ID
TVIS44013146
Fusion event
HTLV-1-LINC01494 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q35
Reference genome
GRCh37/hg19
Start
219780056/218915334 (Hg38)
End
219780056/218915334 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01494
Nearest miRNA
hsa-mir-10b/Upstream/92180; hsa-mir-1244-1/Downstream/86311;
Nearest TSS
ENST00000437798/Upstream/22113; ENST00000302625/Downstream/15302;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/5953, chr2-CpG: 174/Downstream/44095
Upstream sequence
CCTGActccattccaattgtctggaagagtttgtgtagaattggtattatttctttgttaaatgtttagtagaattcactagggaagccaactggacctg
Downstream sequence
aagtgtcctttgtgaaaagatttttagctacacattcaatccctttgatagctatccagttactttgattctctgtttcttgagatttttggtaaatGAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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