Basic Information
VIS ID
TVIS44013177
Fusion event
HTLV-1-chr6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
39114898/39147122 (Hg38)
End
39114898/39147122 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/72741; hsa-mir-10398/Downstream/2451601;
Nearest TSS
ENST00000381078/Upstream/31933; ENST00000405961/Downstream/82328;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/31844, chr6-CpG: 72/Downstream/81919
Nearby gene
SAYSD1(No orient, 31936)
Upstream sequence
cctgtgatggtgaattttgtgtgtcaactaggtgatagtggccagtcatttggtcagacaccagtctagatgttgctatgaaggtattttttagatatga
Downstream sequence
ttaacatttaaatcaatagattttgagtaaagctgattactctccatagtgagtgggcctaatccaatcacatgaaaacttttgaagacatcccctgagt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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