Basic Information
VIS ID
TVIS44013191
Fusion event
HTLV-1-FAAH2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
57337756/57311323 (Hg38)
End
57337756/57311323 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAAH2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7f-2/Upstream/1859741; hsa-mir-105-1/Downstream/6474679;
Nearest TSS
ENST00000429181/Upstream/24617; ENST00000465623/Downstream/120640;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/173888, chrX-CpG: 97/Downstream/280646
Upstream sequence
aaagaaaaaatataataatataacaaaacttatgggatgtagctaaattagtacttagagggaaatgtatggctttcagtgaatatacatgaaaagaaag
Downstream sequence
atttaaaatcagtaactgaagcctggccttaaatggctcctgcgaaaggggtcagtgagggaactgaggcctcaccttcaccaggaatctttgggatcct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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