Basic Information
VIS ID
TVIS44013194
Fusion event
HTLV-1-SPANXA2-OT1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q27.2
Reference genome
GRCh37/hg19
Start
140718819/141630689 (Hg38)
End
140718819/141630689 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRAXD
Target gene
SPANXA2-OT1
Nearest miRNA
hsa-let-7f-2/Upstream/704458; hsa-mir-105-1/Downstream/4362061;
Nearest TSS
ENST00000429181/Upstream/41254; ENST00000483584/Downstream/68050;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/453469, chrX-CpG: 130/Downstream/2002905
Upstream sequence
tccacttcttcaggatgactataagaaGCTCATATACTGCATACtatatatatatatatgcatatatatttatgcatatTATGCATTTATCTAATATATG
Downstream sequence
CATTAGTGGTCATATGAATATGACATTTTATTGTACCAATGTCTCAGCAaacaaatattttatggagtgcctgatatgtgtcagacctgttctaggtcct
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate