Basic Information
VIS ID
TVIS44013198
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
1016421/1081041 (Hg38)
End
1016421/1081041 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/448356; hsa-mir-101-1/Downstream/86063;
Nearest TSS
ENST00000473358/Upstream/6734; ENST00000416774/Downstream/3031;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/61, chr1-CpG: 41/Downstream/442
Nearby gene
C1orf159(No orient, 777)
Upstream sequence
cacctcggtccctgtctccttccctccGCCCCCACCTCGGTCCCTGTCTCCTTCCCTCTGCTCCCATCTCGGTCCCTGTCTCCTTCCCCACAGGAGGAGT
Downstream sequence
CTGGGGGCTCCCGCGTCACAGGGGCGTGGCCCAGGGCATCAGGTGGGGCGGTGGGTACTGGGCTCAGAGTGGCCTTGGGCTGTCCAGTCCCTCCCTTTCT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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