Basic Information
VIS ID
TVIS44013206
Fusion event
HTLV-1-WDR49 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
167316884/167599096 (Hg38)
End
167316884/167599096 (Hg38)
Orient
+
Location type
Intronic
Target gene
WDR49
Nearest miRNA
hsa-let-7g/Upstream/3427540; hsa-mir-1224/Downstream/952758;
Nearest TSS
ENST00000440867/Upstream/23865; ENST00000472941/Downstream/21461;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/218686, chr3-CpG: 37/Downstream/135492
Upstream sequence
tgtggccatcaccactgagactgtgctgggtcagatatgaagccagcacagcactgggtcttgccaaaagcctgctgtaaccattacctggctaccacct
Downstream sequence
atgttttcccacggctctggggctctatggtcagcatgtggttaagcagacaaccttgtgtccttcccttcagggcagttagttccctcaggtcccaggc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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