Basic Information
VIS ID
TVIS44013221
Fusion event
HTLV-1-DSTYK integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q32.1
Reference genome
End
205157143/205188015 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-130b-3p ; hsa-mir-148a-3p ; hsa-mir-192-5p ; hsa-mir-93-5p ; hsa-mir-15a-5p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-6504-3p ; hsa-mir-8080 ; hsa-mir-627-3p ; hsa-mir-877-3p ; hsa-mir-544a ; hsa-mir-6878-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-6872-3p ; hsa-mir-4438 ; hsa-mir-6505-5p ; hsa-mir-5192 ; hsa-mir-4261 ; hsa-mir-875-3p ; hsa-mir-665 ; hsa-mir-4768-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-6882-5p ; hsa-mir-922 ; hsa-mir-3678-3p ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-2467-3p ; hsa-mir-4645-3p ; hsa-mir-3919 ; hsa-mir-3123 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-3127-5p ; hsa-mir-3918 ; hsa-mir-619-5p ; hsa-mir-5004-3p ; hsa-mir-1200 ; hsa-mir-496 ; hsa-mir-432-5p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-5089-5p ; hsa-mir-4279 ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-548q ; hsa-mir-6506-5p ; hsa-mir-1976 ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6814-5p ; hsa-mir-5697 ; hsa-mir-562 ; hsa-mir-4326 ; hsa-mir-498 ; hsa-mir-6888-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-3120-5p ; hsa-mir-3653-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-5571-5p ; hsa-mir-6885-3p ; hsa-mir-29b-2-5p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-19b-2-5p ; hsa-mir-19b-1-5p ; hsa-mir-19a-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-106a-3p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-1304-3p ; hsa-mir-17-5p ; hsa-mir-186-3p ; hsa-mir-20a-5p ; hsa-mir-20b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-302e ; hsa-mir-3622b-5p ; hsa-mir-3664-5p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-4639-3p ; hsa-mir-4663 ; hsa-mir-5186 ; hsa-mir-5197-5p ; hsa-mir-519d-3p ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-520e ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-526b-3p ; hsa-mir-6794-3p ; hsa-mir-7160-5p ; hsa-mir-8077
Nearest miRNA
hsa-mir-101-1/Upstream/3184779; hsa-mir-1182/Downstream/260287;
Upstream sequence
AGAGGAGAAATTTCTAGGAACCTTGGTTGAAGGACATATCAGGGAAAAAACCCCAGTGAGAAAAAGCTCTTCACATATCAAACAGAATTCCTTTCCCTAG
Downstream sequence
CTCACCCCCTAGGAACAAACTGTTATTTCTACCCAGAAATGTGGGAGTGACCTGATCTTCCCGCCCCGCTCCTTTTTCATTCAGTGGAGGGACAGCCTAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate