Basic Information
VIS ID
TVIS44013239
Fusion event
HTLV-1-LOC105371970 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
5360362/5360363 (Hg38)
End
5360362/5360363 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105371970
Nearest miRNA
hsa-mir-6718/Upstream/1474931; hsa-mir-1-2/Downstream/480332;
Nearest TSS
ENST00000575820/Upstream/49967; ENST00000577527/Downstream/24967;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/63263, chr18-CpG: 129/Downstream/182485
Nearby gene
EPB41L3(-32018) ;
Upstream sequence
aaaaagtgggcataacaacatTTACAATCCATCCTTGCTACatttatgttttatagctttttactctctactatactagaacataagctccaccaagata
Downstream sequence
gagatgttatctgtctaaatcacaatgcacctcgtgtatgaaacaaaacctggcatataataagtattgaatatttgcctgctgaatgaatgaatAAATG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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