Basic Information
VIS ID
TVIS44013248
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
43318902/43277410 (Hg38)
End
43318902/43277410 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/4139144; hsa-let-7g/Downstream/836802;
Nearest TSS
ENST00000440867/Upstream/171334; ENST00000462810/Downstream/9102;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/171189, chr3-CpG: 63/Downstream/8796
Nearby gene
SNRK(+9102) ;
Upstream sequence
ctgaaacagctttattgctgatatggtcaaagttttagtggtctggatagaagatcaaaccagccacaatattcccttaagtcaaagcctaattcagagc
Downstream sequence
aaggtcctaactctcttcaattctatgaaggccgagacaggtgaggaagctgcagaaggaagtttgaagctaccagaagttggttcatgaggtttttttt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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