Basic Information
VIS ID
TVIS44013285
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.4
Reference genome
GRCh37/hg19
Start
40279445/40420193 (Hg38)
End
40279445/40420193 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1587/Upstream/582580; hsa-let-7f-2/Downstream/5325964;
Nearest TSS
ENST00000429181/Upstream/157227; ENST00000637954/Downstream/159179;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/152702, chrX-CpG: 103/Downstream/160294
Nearby gene
LOC101927476(No orient, 132471)
Upstream sequence
tgcctcagccttctgagtagctagaacttgaggcatgtgccactatgcctggataatttattttattctttgtagaaacagggtctcactatgttgctca
Downstream sequence
ggccggtctggaactcctggcctcaggctttcctcctgcctcaacttcccaaagcgctgggattacagtcatgagccactgcccctagccCTGTTTTGAG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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