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TVIS44013300
Basic Information
VIS ID
TVIS44013300
Fusion event
HTLV-1-RAPGEF1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
GRCh37/hg19
Start
134554405/131679018 (Hg38)
End
134554405/131679018 (Hg38)
Orient
+
Location type
Intronic
Target gene
RAPGEF1
miRNAs that regulate target gene
hsa-mir-375
;
hsa-mir-615-3p
;
hsa-mir-193b-3p
;
hsa-mir-339-5p
;
hsa-mir-27b-3p
;
hsa-mir-25-3p
;
hsa-mir-4709-3p
;
hsa-mir-4452
;
hsa-mir-3127-5p
;
hsa-mir-5196-5p
;
hsa-mir-4747-5p
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-211-3p
;
hsa-mir-506-5p
;
hsa-mir-9500
;
hsa-mir-6510-5p
;
hsa-mir-6864-5p
;
hsa-mir-561-5p
;
hsa-mir-3175
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-365b-5p
;
hsa-mir-365a-5p
;
hsa-mir-6809-5p
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-3202
;
hsa-mir-3179
;
hsa-mir-7515
;
hsa-mir-6830-5p
;
hsa-mir-4475
;
hsa-mir-541-5p
;
hsa-mir-3646
;
hsa-mir-203a-3p
;
hsa-mir-3941
;
hsa-mir-483-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-5692a
;
hsa-mir-6881-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-6744-5p
;
hsa-mir-942-5p
;
hsa-mir-550b-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-766-3p
;
hsa-mir-6787-3p
;
hsa-mir-877-3p
;
hsa-mir-5193
;
hsa-mir-6849-3p
;
hsa-mir-508-5p
;
hsa-mir-3145-5p
;
hsa-mir-432-3p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6736-3p
;
hsa-mir-185-3p
;
hsa-mir-4722-3p
;
hsa-mir-4763-5p
;
hsa-mir-4769-3p
;
hsa-mir-6727-3p
;
hsa-mir-6798-5p
;
hsa-mir-6805-5p
;
hsa-mir-6817-5p
;
hsa-mir-6829-5p
;
hsa-mir-6846-5p
;
hsa-mir-6848-5p
;
hsa-mir-6882-3p
;
hsa-mir-6894-3p
;
hsa-mir-95-5p
Nearest miRNA
hsa-let-7a-1/Upstream/1052655; hsa-mir-126/Downstream/1266689;
Nearest TSS
ENST00000422679/Upstream/35627;
ENST00000444708/Downstream/30703;
Nearest CpG islands
None/Target,
chr9-CpG: 64/Upstream/123925
,
chr9-CpG: 156/Downstream/60295
Upstream sequence
CATTTCCCCCTGCTTTTTATGAGTGAAACTGGATATGGTTTTGAAGGGCAGTAGCTAGACAAAACAGGCCAGCAGGAGCaggacagattaaaaatgcagg
Downstream sequence
aattcctcagcccggagaagcaaaggctaagaggCAGCAGTGACTGGGGGTGGGGGGAAATGATGAGGAGAATCCTAGGACAAATATGGCCCTAGGGTGC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL149
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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