VISDB Viral Integration Site DataBase

VIS ID

TVIS44013302

Fusion event

HTLV-1-MTDH integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

q22.1

Reference genome

Start

End

98662507/97650279 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-26a-5p ; hsa-mir-375 ; hsa-mir-136-5p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-192-5p ; hsa-mir-30a-5p ; hsa-mir-139-3p ; hsa-mir-30c-5p ; hsa-mir-542-3p ; hsa-mir-34b-5p ; hsa-mir-378a-5p ; hsa-mir-545-5p ; hsa-mir-449c-5p ; hsa-mir-1200 ; hsa-mir-2682-5p ; hsa-mir-3714 ; hsa-mir-140-3p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-26b-5p ; hsa-mir-1297 ; hsa-mir-4465 ; hsa-mir-499a-5p ; hsa-mir-137 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-4531 ; hsa-mir-1273e ; hsa-mir-937-5p ; hsa-mir-6894-5p ; hsa-mir-5702 ; hsa-mir-6840-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-630 ; hsa-mir-552-3p ; hsa-mir-3910 ; hsa-mir-506-3p ; hsa-mir-124-3p ; hsa-mir-5697 ; hsa-mir-4432 ; hsa-mir-8087 ; hsa-mir-653-5p ; hsa-mir-549a ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-506-5p ; hsa-mir-320a ; hsa-mir-302c-3p ; hsa-mir-145-5p ; hsa-mir-145-3p ; hsa-mir-153-3p ; hsa-mir-342-3p ; hsa-mir-22-3p ; hsa-mir-217 ; hsa-mir-4738-3p ; hsa-mir-548g-3p ; hsa-mir-619-5p ; hsa-mir-6807-5p

Nearest miRNA

hsa-mir-12123/Upstream/2577283; hsa-mir-10400/Downstream/743366;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/5277, chr8-CpG: 107/Downstream/125328

Nearest cancer related gene

MTDH(OG, No orient, 0)

Upstream sequence

tttcctgacctcgtgatccgcctgcctcagcctcccaaagtgctgggattacaggcatgagccaccaggcccggccAGTTTCttttcttatttttatttt

Downstream sequence

taaatttcttttcgaaacagggtctggctgtgtcaaccaggctggagtgcagtggcgtaatcttggctcactgcaacctcaacctcccaggctcaagcga