Basic Information
VIS ID
TVIS44013334
Fusion event
HTLV-1-LOC101928859 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
65621443/63861683 (Hg38)
End
65621443/63861683 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
LOC101928859
Nearest miRNA
hsa-mir-1265/Upstream/488635; hsa-mir-107/Downstream/3541668;
Nearest TSS
ENST00000439456/Upstream/197019; ENST00000634479/Downstream/175597;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/230608, chr10-CpG: 30/Downstream/111824
Nearby gene
REEP3(+236560) ;
Upstream sequence
GGCTGATTCTATACATTTAATAACTATTTACCTGGTGTGATTTGGGAGGCATAAAAATTATCTGCCTCAATATAGTTTTTTTTTACCCAAATGATAATAT
Downstream sequence
CTATCTCTAAGATTCATCCTTTTAGGTTAAATATTGCCTCCTTACCTAGTTCTCTTTGTTGGAAGTAGATAATTCATAATGCTACTTATATTTTGGTGTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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