Basic Information
VIS ID
TVIS44013338
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q12.13
Reference genome
GRCh37/hg19
Start
26660846/26086708 (Hg38)
End
26660846/26086708 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/1924204; hsa-mir-1267/Downstream/13577326;
Nearest TSS
ENST00000623511/Upstream/33323; ENST00000621997/Downstream/134983;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/34581, chr13-CpG: 50/Downstream/99576
Nearby gene
SHISA2(-35648) ;
Upstream sequence
ttgccttcttttaaaaaatctactgaggtattgctttttctaattattcatcatagctATCATAAATCCTTTACCCAACTTTTAACTTGTATTTTAACTT
Downstream sequence
AATCTGTGGTCTCCCAGAAATTTGTTTTTATTTTGAATAAATAGGAAACAGAACCCAGTCAAAAAAGAAAACTAAATCAGTCAAATAATGTGTAGGAAAA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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