Basic Information
VIS ID
TVIS44013356
Fusion event
HTLV-1-LOC105377999 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
130208588/129887443 (Hg38)
End
130208588/129887443 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105377999
Nearest miRNA
hsa-mir-10398/Upstream/3402730; hsa-mir-1202/Downstream/1904729;
Nearest TSS
ENST00000381078/Upstream/25896; ENST00000526087/Downstream/126256;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/957269, chr6-CpG: 208/Downstream/131598
Nearby gene
TMEM244(No orient, 26172)
Upstream sequence
attgaaagcaatctgttttataaataggagattagattgatagattgtggccgttcatgcaagggaatatcactcagctgttaaGAAAGGTGACATCTAT
Downstream sequence
TTATCCACCAAGATTTATATATACTATGTATGCAAACCAGCAGCTCAGCTTAGTGAGCAGATTCTGAAGGCTCagtgcagactctggaatcatacccggg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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