Basic Information
VIS ID
TVIS44013381
Fusion event
HTLV-1-chr7 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
19414738/19375115 (Hg38)
End
19414738/19375115 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1302-6/Upstream/1247806; hsa-mir-10399/Downstream/330243;
Nearest TSS
ENST00000635602/Upstream/21581; ENST00000590912/Downstream/325220;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/229705, chr7-CpG: 44/Downstream/333659
Nearby gene
FERD3L(-229694) ;
Upstream sequence
aggacatgaactcatcattttttatggctgcatagtattccatggtgtatatgtgccacattttcttaatccagtctatcattgttggacatttgggttg
Downstream sequence
gttccaagtctttgctgttgtgaatggtgccgcaataaacataggtgtgcatgtgtctttatagcagcatgatttataaccctttgggtatatacccagt
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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