Basic Information
VIS ID
TVIS44013408
Fusion event
HTLV-1-NCAPGP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
30298542/30006339 (Hg38)
End
30298542/30006339 (Hg38)
Orient
-
Location type
Intronic
Target gene
NCAPGP2
Nearest miRNA
hsa-mir-1268a/Upstream/1515494; hsa-mir-10393/Downstream/1058693;
Nearest TSS
ENST00000557528/Upstream/37474; ENST00000568123/Downstream/39509;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/37148, chr15-CpG: 53/Downstream/38102
Nearby gene
TJP1(-37540) ;
Upstream sequence
ATAAAGATCATGCTTTCTCTTACACTCTTTCTTTTAAGTGAAGGAAATTGATTCTAGTGGAAACGTTAACTCCTGAAATTGCTTTGTATTGGTGTGCCCT
Downstream sequence
TTGTGAATATTTGAAATCAAAAGGAGATGAAGGTGAAGAATTTTTAGAGCGGATTTCGCCAGAGCCTGTAGTATATATAGACTATTTACTGAGGTAAATT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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