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TVIS44013425
Basic Information
VIS ID
TVIS44013425
Fusion event
HTLV-1-UBN2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q34
Reference genome
GRCh37/hg19
Start
138995381/139310635 (Hg38)
End
138995381/139310635 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBN2
miRNAs that regulate target gene
hsa-mir-103a-3p
;
hsa-mir-16-5p
;
hsa-mir-10a-5p
;
hsa-mir-100-5p
;
hsa-let-7e-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-101-3p
;
hsa-mir-130a-3p
;
hsa-mir-144-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-937-5p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-548aw
;
hsa-mir-7856-5p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-545-3p
;
hsa-mir-4517
;
hsa-mir-4524a-5p
;
hsa-mir-4524b-5p
;
hsa-mir-6838-5p
;
hsa-mir-150-3p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-590-3p
;
hsa-mir-603
;
hsa-mir-4775
;
hsa-mir-8485
;
hsa-mir-186-3p
;
hsa-mir-653-3p
;
hsa-mir-3168
;
hsa-mir-4263
;
hsa-mir-495-5p
;
hsa-mir-513b-5p
;
hsa-mir-194-3p
;
hsa-mir-1303
;
hsa-mir-133a-5p
;
hsa-mir-889-5p
;
hsa-mir-3652
;
hsa-mir-4430
;
hsa-mir-4505
;
hsa-mir-5787
;
hsa-mir-6842-3p
;
hsa-mir-26a-5p
;
hsa-mir-26b-5p
;
hsa-mir-765
;
hsa-mir-1290
;
hsa-mir-1297
;
hsa-mir-3150b-3p
;
hsa-mir-4465
;
hsa-mir-4784
;
hsa-mir-6757-3p
;
hsa-mir-6834-5p
;
hsa-mir-6888-5p
;
hsa-mir-8068
;
hsa-mir-9500
;
hsa-mir-187-5p
;
hsa-mir-4635
;
hsa-mir-378a-5p
;
hsa-mir-605-3p
;
hsa-mir-6126
;
hsa-mir-218-5p
;
hsa-mir-3942-3p
;
hsa-mir-431-5p
;
hsa-mir-17-3p
;
hsa-mir-4276
;
hsa-mir-4493
;
hsa-mir-5190
;
hsa-mir-5094
;
hsa-mir-3074-3p
;
hsa-mir-3163
;
hsa-mir-6739-3p
;
hsa-mir-375
;
hsa-mir-5089-3p
;
hsa-mir-6734-5p
;
hsa-mir-1226-5p
;
hsa-mir-6509-3p
;
hsa-mir-4540
;
hsa-mir-6723-5p
;
hsa-mir-6894-5p
;
hsa-mir-7154-3p
;
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-548v
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6875-5p
;
hsa-mir-3126-5p
;
hsa-mir-1273g-3p
;
hsa-mir-181a-2-3p
;
hsa-mir-646
;
hsa-mir-5694
;
hsa-mir-383-5p
;
hsa-mir-503-5p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-5702
;
hsa-mir-125b-2-3p
;
hsa-mir-4457
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-3927-5p
;
hsa-mir-454-5p
;
hsa-mir-382-3p
;
hsa-mir-4653-3p
;
hsa-mir-6867-5p
;
hsa-mir-190a-3p
;
hsa-mir-223-5p
;
hsa-mir-511-3p
;
hsa-mir-4803
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-mir-3658
;
hsa-mir-641
;
hsa-mir-3617-5p
;
hsa-mir-208b-3p
;
hsa-mir-208a-3p
;
hsa-mir-499a-5p
;
hsa-mir-4535
;
hsa-mir-4800-5p
;
hsa-mir-659-5p
;
hsa-mir-492
;
hsa-mir-6861-3p
;
hsa-mir-600
;
hsa-mir-5693
;
hsa-mir-574-5p
;
hsa-mir-4455
;
hsa-mir-5701
;
hsa-mir-197-3p
;
hsa-mir-4717-3p
;
hsa-mir-4640-3p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-640
;
hsa-mir-1193
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-6747-3p
;
hsa-mir-2392
;
hsa-mir-4662a-5p
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-6778-3p
;
hsa-mir-6715b-3p
;
hsa-mir-16-1-3p
;
hsa-mir-6715a-3p
;
hsa-mir-4789-3p
Nearest miRNA
hsa-mir-10399/Upstream/266478; hsa-mir-11400/Downstream/3163892;
Nearest TSS
ENST00000635602/Upstream/17008;
ENST00000482181/Downstream/28822;
Nearest CpG islands
None/Target,
chr7-CpG: 39/Upstream/78425
,
chr7-CpG: 108/Downstream/29549
Nearby gene
UBN2
(+2399) ;
Upstream sequence
caagggaggcggatcacttgaggtcaggagttagaaactaacctggccaacatggtgaaaccccgtctctaccaaaaatacaaaaaaatcagctgggcat
Downstream sequence
ggtgactcatgtctgtaatcccagctactcaggaggctaaggcaggagaatcgcttgcacctaggaggcagaggttgcagtgagccgagatcgtgctact
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL227
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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