Basic Information
VIS ID
TVIS44013490
Fusion event
HTLV-1-LOC105378797 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
72836669/72370986 (Hg38)
End
72836669/72370986 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
LOC105378797
Nearest miRNA
hsa-mir-101-1/Upstream/1303270; hsa-mir-11399/Downstream/4689157;
Nearest TSS
ENST00000473358/Upstream/88252; ENST00000418078/Downstream/394045;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/86933, chr1-CpG: 24/Downstream/1827156
Nearby gene
NEGR1(-88392) ;
Upstream sequence
ggcagaggaatgtggaaagactagactgtttgagtcttccggcctccacatttctccctggctggatgctttctgcccttaaacatcagactccaagtac
Downstream sequence
ttcagcttttggactcttggacttataccagtgattcaccagggactttcaggcctttggctgcagagtgaaggctacactatccgcttttctacttttg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate