Basic Information
VIS ID
TVIS44013536
Fusion event
HTLV-1-BAGE integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
11082084/10430371 (Hg38)
End
11082084/10430371 (Hg38)
Orient
+
Location type
Intronic
Target gene
BAGE
Nearest miRNA
hsa-mir-10396a/Upstream/1442706; hsa-let-7c/Downstream/2976013;
Nearest TSS
ENST00000624081/Upstream/87634; ENST00000612957/Downstream/91182;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/24633, chr21-CpG: 159/Downstream/90672
Upstream sequence
AAGTTTTGTTCTGTTTTTAATTCACAATGAAAATCTGACTactcatttattcaacaaatatttgagtaccagctatgtgctaggcactgttctaaacacA
Downstream sequence
CCAATAACATTTATTTAGTGGTACTGATTCTGTACTCTAGAAcaatggctcttaactggggagagggagcaatttttgctgcccaagggacatctggcaa
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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