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VISDB
Viral Integration Site DataBase
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TVIS44013541
Basic Information
VIS ID
TVIS44013541
Fusion event
HTLV-1-PDIA5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
122811109/123092262 (Hg38)
End
122811109/123092262 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDIA5
miRNAs that regulate target gene
hsa-mir-26b-5p
;
hsa-mir-513a-5p
;
hsa-mir-6124
;
hsa-mir-3148
;
hsa-mir-3688-3p
;
hsa-mir-382-3p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-128-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
Nearest miRNA
hsa-let-7g/Upstream/2042547; hsa-mir-12124/Downstream/69532;
Nearest TSS
ENST00000440867/Upstream/3155;
ENST00000472319/Downstream/31804;
Nearest CpG islands
None/Target,
chr3-CpG: 148/Upstream/24509
,
chr3-CpG: 46/Downstream/109594
Upstream sequence
AGAGCCAGGACCATTCTTGCAGCACAGGCCCTAGCACTGTTGAATGCAGGGATGGGTGTTTTACCTGGTGCTCAGGACTTCTCCACCCCCTCTAGGATTG
Downstream sequence
GTCTCCATCCTTCCTCACCCCTGAGGGAAGATAGCAGACATGACCCAGTGCCCTTGGTCACAGATGTTTAATTTTTTGTTTTTTTTTTACAGAGGTGGCA
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Sample Information
×
Sample name
ATL3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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