Basic Information
VIS ID
TVIS44013577
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
142996981/141915620 (Hg38)
End
142996981/141915620 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA8D
Nearest miRNA
hsa-mir-1204/Upstream/129307; hsa-mir-10400/Downstream/260719;
Nearest TSS
ENST00000518652/Upstream/400923; ENST00000562989/Downstream/174207;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/12328, chr8-CpG: 28/Downstream/57803
Nearby gene
MIR4539(No orient, 82656)
Upstream sequence
cattctattttcagaggttggaaggatcagtatggaaaatgtcaattcctcaaaattcatttataaattcaatgcaataatacaaaacctcataattttt
Downstream sequence
gatacaaaatctgccaaactctaaaataagtatgagaatgcaaagggccctaaatcatcaatactctcaaaaattagtgacgtaggcagacttgtccttc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate