Basic Information
VIS ID
TVIS44013586
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
164167864/164198627 (Hg38)
End
164167864/164198627 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/1855987; hsa-mir-1182/Downstream/1709294;
Nearest TSS
ENST00000473358/Upstream/858372; ENST00000485769/Downstream/356957;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/775317, chr1-CpG: 34/Downstream/122651
Nearby gene
PBX1(+360733) ;
Nearest cancer related gene
PBX1(OG, +360733) ;
Upstream sequence
aaaaactggaggcattccctttgaaaactggcacaagaaaaggatgccctctctcaccactcctattcaaaatagtattggaagttttggccagaggaat
Downstream sequence
caggcaagagaaacaaataaagggtattcaattaggaaaagaggaagtcaaattacctctgtttgcagatgacatgattgtatatttagaaaacgccatc
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate