Basic Information
VIS ID
TVIS44013622
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
19641072/19599580 (Hg38)
End
19641072/19599580 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/284649; hsa-let-7g/Downstream/537985;
Nearest TSS
ENST00000440867/Upstream/251859; ENST00000443878/Downstream/299244;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/450972, chr3-CpG: 87/Downstream/347261
Nearby gene
KCNH8(+63937) ;
Upstream sequence
ATGTAATTTcacctacagtgaactcatttttgacaaaggtgccaagaacatgcattggcgaaaaggcagtgtctaaaataaatgatgccagaaaaactgg
Downstream sequence
atatccatacacagaaaaatgaacctagatccctatctctcaccctatagtaaaatcaaaatcaaaatggattaaagacttaaaactaagacccaaaacg
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate