Basic Information
VIS ID
TVIS44013641
Fusion event
HTLV-1-LINC01599 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
50533932/50067214 (Hg38)
End
50533932/50067214 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01599
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-208a/Upstream/100703; hsa-mir-1185-1/Downstream/232641;
Nearest TSS
ENST00000550708/Upstream/25985; ENST00000426751/Downstream/21961;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/63513, chr14-CpG: 60/Downstream/49038
Upstream sequence
CAGAGGCTTCTGAACTATGCGAGATGCAGGAAGCATTTTCTGAAAGAGAGTCCCTCTTAGGGGAAGATACCAGAGTCTGCTTACCAGAAACATCAAGAGG
Downstream sequence
GGAGGCAGCTGCAGAAATGAATGTGGACAGAAACACTGAACGCAGCAATTTATAAAAGAGGCTACTTTGGTCTCCTGGATACGTGTTTCTTTTTTCTTAC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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