Basic Information
VIS ID
TVIS44013660
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
42730593/41358666 (Hg38)
End
42730593/41358666 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/191037; hsa-mir-5692b/Downstream/388106;
Nearest TSS
ENST00000624081/Upstream/35846; ENST00000494252/Downstream/3277;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/41508, chr21-CpG: 29/Downstream/61700
Nearby gene
FAM3B(+939) ;
Upstream sequence
CCAAGCAGTGCTCTGGCCCAGGGAGGAGCATCACCCAGCCTGCAAGCCCTGCCCTGGGCAGAGGCCCCTCAGGGAGCCTGGTTGTCTGCAAGGAAGGCTG
Downstream sequence
CAAACCACTGGATGGGGTCATGGCTCAGATCCCAGtaggggctgaactgtatcccccaaaattcatctgctgaagtcctaacccccagaatgcaacctta
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate