Basic Information
VIS ID
TVIS44013686
Fusion event
HTLV-1-ANOS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
8534408/8566367 (Hg38)
End
8534408/8566367 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANOS1
Nearest miRNA
hsa-mir-3690-1/Upstream/439306; hsa-let-7f-2/Downstream/2752247;
Nearest TSS
ENST00000429181/Upstream/29431; ENST00000432442/Downstream/4283;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/638800, chrX-CpG: 144/Downstream/164449
Upstream sequence
AAAATTAGGCACTTTTAAGGCAGAAACCAAAATACATCATCGTGCTAGGAATAAtgtatgtgtgtgtatatatgtgtgtgtgtgtgtgtgtatgagtatg
Downstream sequence
tatgtgtgtatagttatgtgcgtgtttgtgtatatttgtagacacatgtgtatatgtatgcatatgtgtacatatatacctatgtgcatactatttatag
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate