Basic Information
VIS ID
TVIS44013688
Fusion event
HTLV-1-chr1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37/hg19
Start
80081486/79615801 (Hg38)
End
80081486/79615801 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/2555599; hsa-mir-11399/Downstream/5517993;
Nearest TSS
ENST00000473358/Upstream/290793; ENST00000567886/Downstream/435603;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/608949, chr1-CpG: 24/Downstream/715171
Nearby gene
ADGRL4(No orient, 608991)
Upstream sequence
TGCTTGAAATGTTTGCCTCACATGTTTGATATGAAGTTTGGAGTCTATAAAAACACCGCTTCTGAACTGTTTTGCACAGGTAGATGTCCAAGTATTTTGT
Downstream sequence
CAGCAAAAATGCATTATTAACGAATGACAATTGGAATAAAAAGAGCTTTAAGAATATAGAATCATACGTTACTTATAAAGGAAATAATTTCAACTAATGT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate