Basic Information
VIS ID
TVIS44013706
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
110443154/109790807 (Hg38)
End
110443154/109790807 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1267/Upstream/2259559; hsa-mir-4502/Downstream/550151;
Nearest TSS
ENST00000623511/Upstream/4239; ENST00000614629/Downstream/14510;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2974, chr13-CpG: 23/Downstream/78825
Nearby gene
IRS2(-4240) ;
Nearest cancer related gene
IRS2(OG, -4240) ;
Upstream sequence
ACATAAATGCCCAATTAAAAAGTGACTGCGGTTAGGAGTTGAAAATATTTATTAATATGCCTCTGGATTTTGTTCTGTTTGAATTTTGAGAATGTGTTTC
Downstream sequence
TAGATTTAAGAAGCAACACAAGCTTTTTTTCCCAGAAGGCTTCCTATTATTGAAATGGAAATTATACATTAATGACTGTATAACACTAGTAGATATTTTT
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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