Basic Information
VIS ID
TVIS44013744
Fusion event
HTLV-1-MIR548T integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
147933732/148236640 (Hg38)
End
147933732/148236640 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA7I
Target gene
MIR548T
Nearest miRNA
hsa-mir-10399/Upstream/858519; hsa-mir-153-2/Downstream/3001781;
Nearest TSS
ENST00000635602/Upstream/64256; ENST00000602734/Downstream/26415;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2119648, chr7-CpG: 33/Downstream/102762
Upstream sequence
ttttgaagaactttccttaaagctacttaggcatttagtctgccttccaggttatgtgaggtgacagttttacaaaatattttattgcatactatattag
Downstream sequence
tctgtcttgcactgctataaagaaatacctgagactgagtaattcataaagaaaaaaaaggtttagttggctcacagttctgcaggctgtacaagacgca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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