Basic Information
VIS ID
TVIS44013764
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
118894460/119023750 (Hg38)
End
118894460/119023750 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11B
Nearest miRNA
hsa-mir-10392/Upstream/112963; hsa-let-7a-2/Downstream/289200;
Nearest TSS
ENST00000527297/Upstream/1982; ENST00000531886/Downstream/5284;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4345, chr11-CpG: 73/Downstream/6526
Nearby gene
TRAPPC4(+75) ;
Upstream sequence
TTCCTTTGATCTTGGTGTTTGCAATCTGTCTTAATCGATGGTTTTGGGGGAAAGATACAGGAAGTGAGTCAAAAATGGTTAGGGAATTCTGGGAAGATGA
Downstream sequence
TTATGTGCTAGTAAAAAACATAACAAATATGTGTTCATTAAATAAATGAACATAAGATTTTGAAGCATGAGCATTGGATCTAGTCCCAGAATTGCTGCTG
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate