VISDB Viral Integration Site DataBase

VIS ID

TVIS44013774

Fusion event

HTLV-1-RAB8B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

Adult T-cell leukemia (ATL)

Quality evaluation

Normal

Reported year

2014

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr15

Cytoband

q22.2

Reference genome

Start

End

63510835/63218636 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-361-5p ; hsa-mir-128-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-9-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-3973 ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-548aw ; hsa-mir-369-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-1252-3p ; hsa-mir-520f-3p ; hsa-mir-1909-5p ; hsa-mir-5680 ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-298 ; hsa-mir-302c-3p ; hsa-mir-6516-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10393/Upstream/394595; hsa-mir-11181/Downstream/652294;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/28681, chr15-CpG: 23/Downstream/58461

Upstream sequence

CATTCTGGATTGTTTTAAGCTGGAGTCATTTATTTTGCAGGCAATTATTTCCTCATTTAAAGGGCATAGTCCCACTTCATTCATTTGAAATGATGTCAGT

Downstream sequence

TACCACACTACTGAACTCTTCTGGCCTTTTGTGATGGGCGTTTCTCTCTTTTGTTTCTTGGCCTTAGGCTGATAAATCAAAGTATCTCAGGTGATACAGG