Basic Information
VIS ID
TVIS44013782
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
72784003/75072047 (Hg38)
End
72784003/75072047 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/2218665;
Nearest TSS
ENST00000575820/Upstream/956; ENST00000613588/Downstream/1496;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/473319, chr18-CpG: 23/Downstream/15640
Nearby gene
ZNF407(+6375) ;
Upstream sequence
AGGTCCcagaggtgcaatcctaaaatggacaggctgctcttggagaaaaggcgccctccaggcctggaagactctagcagaggctggtgggctcgataga
Downstream sequence
gacacacagtctagaagggcgtcctCGCCGGGCCCGCCTGGCCCTGGGGCCACCAGGGCGTGTTCTGCAGTTCTGGGAAGCGGATCTGCTGACTGGGTCC
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
Curate