Basic Information
VIS ID
TVIS44013783
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
Adult T-cell leukemia (ATL)
Quality evaluation
Normal
Reported year
2014
PubMed ID
24735963
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
6489803/6489792 (Hg38)
End
6489803/6489792 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-1227/Upstream/73281; hsa-let-7e/Downstream/246920;
Nearest TSS
ENST00000633603/Upstream/7235; ENST00000599292/Downstream/4528;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/12676, chr19-CpG: 79/Downstream/5472
Nearby gene
TUBB4A(No orient, 4527)
Upstream sequence
ggttgtggagCTATACATTTTATTTTCATGAATTCGTGTTCTTTGTTGGACCCATTTCCAGGTCatagttctggtaactgcctctttgttctccaccttt
Downstream sequence
ctccctatacaaaggagctgctccttggtgacccagctctgtggtgtCACGAGGGTCCTACCTATTCCGGGgctgctcaatctgtggtcttattcacaca
Reference
Cook, L. B., et al. The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma. Blood,2014, 123(25): 3925-3931.
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